Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

按检索

Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains

Institution:	3. 3Department of Medical Biology, Amsterdam UMC, location AMC, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands;4. 4Department of Biochemistry, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;5. 5Leibniz-Forschungsinstitut für Molekulare Pharmakologie im Forschungsverbund Berlin, Robert-Roessle-St. 10 13089 Berlin, Germany

Abstract:	Download : Download high-res image (74KB) Download : Download full-size image Highlights •Quantitative changes in global proteome and ubiquitinome in Huntington's disease. •Differential ubiquitination of wild-type and mutant Htt in mice brain. •Enriched pathways include vesicle transport and mRNA processing. •Correlation between protein and diGly site fold changes.

Keywords:	Label-free quantification Mass Spectrometry Neurodegenerative diseases Post-translational modifications Ubiquitin Huntington
本文献已被 ScienceDirect 等数据库收录！