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Global Properties of Infectious Disease Models with Nonlinear Incidence
Authors:Andrei Korobeinikov
Affiliation:Laboratory of Nonlinear Science and Computation, Research Institute for Electronic Science, Hokkaido University, Sapporo, 060-0812, Japan. andrei@nsc.es.hokudai.ac.jp
Abstract:
We consider global properties for the classical SIR, SIRS and SEIR models of infectious diseases, including the models with the vertical transmission, assuming that the horizontal transmission is governed by an unspecified function f(S,I). We construct Lyapunov functions which enable us to find biologically realistic conditions sufficient to ensure existence and uniqueness of a globally asymptotically stable equilibrium state. This state can be either endemic, or infection-free, depending on the value of the basic reproduction number.
Keywords:Direct Lyapunov method  Lyapunov function  Endemic equilibrium state  Global stability  Nonlinear incidence
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