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Disassembly of microtubules by the action of calmodulin-dependent protein kinase (Kinase II) which occurs only in the brain tissues
Authors:T Yamauchi  H Fujisawa
Institution:Department of Biochemistry, Asahikawa Medical College, Asahikawa 078-11, Japan
Abstract:Microtubules assembled by the incubation of GTP at 37 °C were disassembled by the action of calmodulin-dependent protein kinase (Kinase II) which occrs only in the brain tissues. This disassembly required the presence of ATP and physiological concentrations of Ca2+ and calmodulin.
Keywords:MAP 2  microtubule-associated protein 2  Mes  EGTA  ethylene glycol bis(β-aminoethyl ether)-N  N  N′  N′-tetraacetic acid
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