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Synthesis of Photoreactive Tryptophan Analogs: Enzymatic Conversion of Azidoindoles to Azidotryptophans
Authors:A. Saito  H. C. Rilling
Affiliation:1. Department of Biochemistry , University of Utah School of Medicine , Salt Lake City, Utah, 84108;2. Department of Chemistry , Brown University Providence , Rhode, 02912, Island
Abstract:Four photoreactive azidoindoles, 4, 5, 6, and 7 azidoindole, were synthesized and converted to the corresponding azidotryptophans by a crude enzyme preparation of tryptophan synthetase from Neurospora crassa.
Keywords:
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