The Purification of Amyloid Fibril Proteins |
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| Authors: | George G Glenner Minoru Harada Chaviva Isersky |
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| Institution: | Laboratory of Experimental Pathology , National Institute of Arthritis and Metabolic Diseases National Institutes of Health , Bethesda, Maryland, 20014 |
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| Abstract: | Amyloid fibril concentrates have been fractionated and shown to have homogeneous fragments of the variable region of immunoglobulin proteins as their major protein constituent. Amyloid fibril protein purification was performed on ten amyloid preparations by sequential gel filtration on Sepharose 4 B and Sephadex G-100 columns equilibrated with 5 M guanidine-HCl in 1 N acetic acid. |
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| Keywords: | Tritirachium sp HKI 0317 Neuropogon sp Diphenylether Macrotriolides |
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