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Pro region engineering of nerve growth factor by deep mutational scanning enables a yeast platform for conformational epitope mapping of anti‐NGF monoclonal antibodies
Authors:Angélica V. Medina‐Cucurella  Yaqi Zhu  Scott J. Bowen  Lisa M. Bergeron  Timothy A. Whitehead
Affiliation:1. Department of Chemical Engineering and Materials Science, Michigan State University Engineering Building, East Lansing, Michigan;2. Zoetis Global Therapeutic Research, Veterinary Medicine Research and Development, Kalamazoo, Michigan;3. Department of Biosystems and Agricultural Engineering, Michigan State University, East Lansing, Michigan;4. Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan
Abstract:
Keywords:conformational epitope mapping  deep mutational scanning  nerve growth factor  pro region  tanezumab  yeast display
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