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Selective mitochondrial accumulation of cytotoxic dinuclear polypyridyl ruthenium(II) complexes
Authors:Pisani Michelle J  Weber Daniel K  Heimann Kirsten  Collins J Grant  Keene F Richard
Affiliation:School of Physical, Environmental and Mathematical Sciences, University of New South Wales, Australian Defence Force Academy, Canberra, ACT 2600, Australia.
Abstract:The lipophilic ligand-bridged dinuclear cation Rubb?? is significantly cytotoxic and preferentially accumulates in the mitochondria of the L1210 murine leukemia cancer cell line.
Keywords:
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