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Phospholipid methylation in pancreatic islets |
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| Authors: | M Saceda P García-Morales J M Mato W J Malaisse I Valverde |
| Abstract: | Glucose provokes a transient stimulation of phospholipid methylation in rat pancreatic islets, possibly by increasing phospholipid methyltransferase activity. The association of DL-homocysteine and 3-deazaadenosine inhibits phospholipid methylation. The methylation of phospholipids may play a role in the stimulus-secretion coupling for glucose-induced insulin release. |
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