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Longitudinal survey of <Emphasis Type="Italic">Staphylococcus aureus</Emphasis> in cystic fibrosis patients using a multiple-locus variable-number of tandem-repeats analysis method |
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| Authors: | Hoang Vu-Thien Katia Hormigos Gaëlle Corbineau Brigitte Fauroux Harriet Corvol Didier Moissenet Gilles Vergnaud Christine Pourcel |
| Institution: | 1.H?pital Armand Trousseau,Assistance Publique-H?pitaux de Paris (AP-HP),Bactériologie,France;2.Université Paris Sud 11, CNRS, UMR 8621,Institut de Génétique et Microbiologie,Orsay,France;3.H?pital Armand Trousseau,Assistance Publique-H?pitaux de Paris (AP-HP),Paris,France;4.DGA/MRIS- Mission pour la Recherche et l'Innovation Scientifique,Bagneux,France |
| Abstract: | BackgroundStaphylococcus aureus infection in patients with cystic fibrosis (CF) is frequent and may be due to colonization by a few pathogenic lineages. Systematic genotyping of all isolates, methicillin-susceptible S. aureus (MSSA) as well as methicillin-resistant S. aureus (MRSA) is necessary to identify such lineages and follow their evolution in patients. Multiple-locus variable-number tandem repeat analysis (MLVA/VNTR) was used to survey S. aureus clinical isolates in a French paediatric CF centre. |
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