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Setting the stage for S phase
Authors:Wilson Angus C
Institution:Department of Microbiology and NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA. wilsoa02@nyu.edu
Abstract:In a recent issue of Molecular Cell, Tyagi et al. (2007) show that E2F1, a positive regulator of S phase entry, recruits cofactor HCF-1 and associated hSet1/MLL histone H3 lysine 4 methyltransferase complex, facilitating the activation of genes required for proliferation.
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