Syntheses and preliminary pharmacological evaluation of the two epimers of the 5-F2t-isoprostane. |
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| Authors: | T Durand J L Cracowski A Guy J C Rossi |
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| Affiliation: | UMR C.N.R.S. 5074, Université Montpellier 1, Faculté de Pharmacie, 15 Av. C. Flahault, F-34060 Cedex 2, Montpellier, France. froxy@pharma.univ-montp1.fr |
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| Abstract: | The total synthesis of the 5-F2t-isoprostane 1 and its 5-epimer 2 from diacetone-D-glucose is described. We report preliminary data on the vascular properties of these compounds. |
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