Integration mechanisms of transgenes and population fitness of GH transgenic fish |
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Authors: | Wei Hu ZuoYan Zhu |
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Institution: | HU Wei & ZHU ZuoYan* State Key Laboratory of Freshwater Ecology , Biotechnology,Institute of Hydrobiology,Chinese Academy of Sciences,Wuhan 430072,China |
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Abstract: | It has been more than 20 years since the first batch of transgenic fish was produced. Five stable germ-line transmitted growth hormone (GH) transgenic fish lines have been generated. This paper reviews the mechanisms of integration and gene targeting of the transgene, as well as the viability, reproduction and transgenic approaches for the reproductive containment of GH-transgenic fish. Further, we propose that it should be necessary to do the following studies, in particularly, of the breeding of transgeni... |
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Keywords: | transgene integration mechanism GH transgenic fish population fitness |
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