Coffee Consumption and Risk of Fracture in the Cohort of Swedish Men (COSM) |
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| Authors: | Helena Hallstr?m Alicja Wolk Anders Glynn Karl Micha?lsson Liisa Byberg |
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| Institution: | 1. Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden.; 2. Institute of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden.; 3. Risk and Benefit Assessment Department, National Food Agency, Uppsala, Sweden.; Loyola University Medical Center, United States of America, |
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| Abstract: | BackgroundRecent research in a large cohort of women showed that coffee consumption is not associated with increased risk of fracture. Whether this is the case also among men is less clear.MethodsIn the Cohort of Swedish Men (COSM) study, 42,978 men aged 45–79 years old at baseline in 1997 answered a self-administered food frequency questionnaire covering coffee consumption and a medical and lifestyle questionnaire covering potential confounders. Our main outcomes first fracture at any site and first hip fracture were collected from the National Patient Registry in Sweden. The association between coffee consumption and fracture risk was investigated using Cox’s proportional hazards regression.ResultsDuring a mean follow-up of 11.2 years, 5,066 men had a first fracture at any site and of these, 1,186 (23%) were hip fractures. There was no association between increasing coffee consumption (per 200 ml) and rate of any fracture (hazard ratio HR] 1.00; 95% confidence interval CI] 0.99–1.02) or hip fracture (HR 1.02; 95% CI 0.99–1.06) after adjustment for potential confounders. For men consuming ≥4 cups of coffee/day compared to those consuming <1 cup of coffee/day, HR for any type of fracture was 0.91 (95% CI 0.80–1.02) and for hip fracture: 0.89 (95% CI 0.70–1.14).ConclusionsHigh coffee consumption was not associated with an increased risk of fractures in this large cohort of Swedish men. |
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