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Reactive derivatives of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene cause S1 nuclease sensitive sites in DNA and "UV-like" repair. |
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| Authors: | R H Heflich D J Dorney V M Maher J J McCormick |
| Institution: | Carcinogenesis Laboratory, College of Osteopathic Medicine Michigan State University, East Lansing, Michigan 48824, USA |
| Abstract: | |
| Keywords: | XP xeroderma pigmentosum UV ultraviolet radiation BP benzo (a)pyrene BPdiol epoxide I(±)-7α 8β -dihydroxy-9β 10β -epoxy-7 8 9 10-tetrahydrobenzo(a)pyrene BP diol epoxide II(±)-7β 8α-dihydroxy-9β 10β-tetrahydrobenzo(a) pyrene 7-BrMeBA 7-bromethylbenz(a)anthracene MNNG N-methyl-N′-nitro-N-nitrosoguanidine N-AcO-AAF N-acetoxy-2-acetylaminofluorene SSC standard saline citrate (0 15 M NaCl 0 017 M NaCitrate pH 7 2) |
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