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New bioactive macrocyclic diterpenoids from Jatropha multifida
Authors:Kanth Boddu Shashi  Kumar Avula Satya  Shinde Digambar Balaji  Babu Kothapalli Hari  Raju Tuniki Venugopal  Kumar Chityal Ganesh  Sujitha Pombala  Das Biswanath
Affiliation:Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 607, India.
Abstract:
Two new macrocyclic diterpenoids, multifidanol (1) and multifidenol (2) along with several known compounds have been isolated from the stem of Jatropha multifida. The structures of the new compounds were established from the extensive studies of their 1D and 2D NMR spectra. The cytotoxic and antimicrobial activities of these two constituents were examined.
Keywords:Multifidanol   Multifidenol   Jatropha multifida   Diterpenoid   Cytotoxicity   Antimicrobial activity
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