PIII 改性ePTFE 膜对细菌生存状态的影响研究

目的:探讨等离子注入技术(Plasma immersion ion implantation,PⅢ)对膨体聚四氟乙烯(ePTFE)膜改性后表面性能以及对细菌生存状态的影响.方法:采用氧等离子注入技术(PⅢ)对ePTFE膜表面处理,获得改性ePTFE膜,利用扫描电镜(SEM)观察改性ePTFE膜和未处理膜的表面形貌,体外培养变形链球菌,观察改性前后各组膜作体外细菌生存状态变化.结果:与未处理ePTFE膜相比,改性ePTFE膜表面形貌、亲水性发生改变.荧光染色后观察长脉冲组表面的细菌最少；短脉冲组膜表面粘附的细菌密集,形成生物膜；空白组可见少量死菌和活菌粘附于ePTFE膜上.结论:长脉冲PⅢ改性ePTFE膜后有良好的抗细菌粘附能力.

Surface Modification of Expanded Polytetrafluoroethylene Membrane by Oxygen Plasma Immersion Ion Implantation and its Survival Condition

Objective: The study aimed at the surface modification of oral biomaterials(expanded polytetrafluoro-ethylene,ePTFE) by means of oxygen plasma immersion ion implantation(PIII) and evaluating its survival condition.Methods: PIII had been used to modify the surface of ePTFE membrane,and the modified ePTFE samples were investigtaied by scanning electron microscopy(SEM).Its survival condition to the modified ePTFE was studied.Results: It revealed that PIII changed surface morphology and water contact angle of ePTFE.The bacteria survival condition indicated that after fluorescence-labeling,less bacteria in long pulse PIII ePTFE,and more bacte-ria in short pulse PIII ePTFE and virgin samples.Conclusion: It manifested that long pulse PIII treated ePTFE significantly reduced the bacterial adhesion in vitro.