左西孟旦治疗心脏术后左心室收缩功能低下

目的:明确左西孟旦治疗心脏术后左心室收缩功能低下的效果。方法:随即抽取2009年6月至今手术治疗后左室射血分数小于35%的患者,分为治疗组和对照组,各25例,给与不同治疗方案。比较两组患者治疗后效果;呼吸状况和全身状况;再次气管插管例数和监护室滞留时间;治疗后左心室射血分数(LVEF)、小轴短缩率(LVFS)。结果:治疗组和对照组分别有3例和5例因心力衰竭死亡。两组患者治疗后再次气管插管例数无统计学差异。与对照组比较,治疗组患者监护室滞留时间短、呼吸状况和全身状况较好(P<0.05),LVEF和LVFS较高有统计学意义(P<0.05)。结论:左西孟旦治疗心脏术后左心室收缩功能低下安全有效,缓解症状明显。

Treatment of Levosimendan in Patients with Left Ventricular SystolicDysfunction Postcardiotomy

Objective:To identify the effect of Levosimendan in patients with left ventricle systolic dysfunction postcardiotomy.Methods: Patients with LVEF below 35% postcardiotomy were randomly grouped as treatment group(25cases) and control group(25cases) since May 2009.Different treatment methods were used for the two groups.The clinical records from two groups were compared in terms of treatment effect,condition of respiratory and whole body,ICU time,frequency of re-intubation and left ventricular ejection fraction(LVEF) and left ventricular short-axis fractional shortening(LVFS).Results: Three cases in treatment group and five cases in control group died of heart failure.There was no statistical difference between the two groups in frequency of re-intubation.Compared with control group,treatment group had shorter time of ICU stay(P < 0.05),and better condition of respiratory and whole body(P < 0.05).Treatment group had a significantly higher LVEF and LVFS than control group.(P < 0.05) Conclusion: The applications of Levosimendan in patients with left ventricle systolic dysfunction postcardiotomy are safe and effective,and it can relieve symptom obviously.