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| 一种植物生长激素-N'-(5-硝基-2-羟基苯亚甲基)-3,5-二羟基苯甲酰肼的合成、晶体结构和抗菌活性 | |
| 引用本文： | 张娅南,黄珊珊,周琴,潘韬文,王明东,刁云鹏.一种植物生长激素-N'-(5-硝基-2-羟基苯亚甲基)-3,5-二羟基苯甲酰肼的合成、晶体结构和抗菌活性[J].现代生物医学进展,2009,9(8). |
| 作者姓名： | 张娅南 黄珊珊 周琴 潘韬文 王明东 刁云鹏 |
| 作者单位： | 1. 大连市中心医院药剂科,辽宁,大连,116033 2. 大连医科大学药学院,辽宁,大连,116044 3. 辽宁省食品药品监督管理局技术审评中心,辽宁,沈阳,110032 4. 大连医科大学药学院,辽宁,大连,116044;辽宁省食品药品监督管理局技术审评中心,辽宁,沈阳,110032;辽宁中医药大学药学院,辽宁,大连,116001 |
| 基金项目： | the,Science,and,Technology,of,Dalian |
| 摘 要： | 目的:合成并表征一种属于植物生长激素的席夫碱类化合物.方法:由5-硝基水杨醛和3,5-二羟基苯甲酰肼在甲醇溶液中反应得到N′-(5-硝基-2-羟基苯亚甲基)-3,5-二羟基苯甲酰肼.结果:用单晶X-射线衍射法测得其结构并表征,同时通过抗菌实验证明其在一定浓度下具有明显的抗菌活性.结论:这种席夫碱类化合物在某种程度上具有明显的抗菌活性. |
| 关 键 词： | 席夫碱 晶体结构 抗菌活性 N'-(5-硝基-2-羟基苯亚甲基)-3 5-二羟基苯甲酰肼 |
A Plant Growth Hormone-Synthesis, Crystal Structure and Antibacterial Activities of N'-(5-nitro-2- hydroxybenzylidene)-3,5-dihydroxybenzohydrazide |
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| ZHANG Ya-nan,HUANG Shan-shan,ZHOU Qin,PAN Tao-wen,WANG Ming-dong,DIAO Yun-peng.A Plant Growth Hormone-Synthesis, Crystal Structure and Antibacterial Activities of N'-(5-nitro-2- hydroxybenzylidene)-3,5-dihydroxybenzohydrazide[J].Progress in Modern Biomedicine,2009,9(8). | |
| Authors: | ZHANG Ya-nan HUANG Shan-shan ZHOU Qin PAN Tao-wen WANG Ming-dong DIAO Yun-peng |
| Abstract: | Objective: A plant growth hormone, known as Schiff base compound, has been synthesized and characterized. Meth-ods: N'- (5-nitro-2-hydroxybenzylidene)-3, 5-dihydroxybenzohydrazide, has been prepared by the reaction of 5-nitrosalicylaldehyde and 3,5-dihydroxybenzohydrazide in methanol solution. Results: The structure of the compound has been characterized by single-crystal X-ray diffraction, and it has moderately antibacterial activity when the concentration has been increased. Conclusions: The compound has possessed antibacterial activity to some extent. |
| Keywords: | Schiffbase Crystal structure Antibacterial activity N'-(5-nitro-2-hydroxybenzylidene) -3 5-dihydro-xybenzohydrazideCharacterization and Bioactivities of the Taurine Schiff base Complexes (No 2008E11SF168) |
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