Cell cycle related proteins in hyperplasia of usual type in breast specimens of patients with and without breast cancer |
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Authors: | Luciene SA Tafuri Gislene FS Rocha Helenice Gobbi |
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Institution: | (1) Department of Anatomic Pathology, School of Medicine, Federal University of Minas Gerais, Av. Alfredo Balena, 190, Belo Horizonte, Minas Gerais, 30150-270, Brazil |
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Abstract: | Background Hyperplasia of usual type (HUT) is a common proliferative lesion associated with a slight elevated risk for subsequent development
of breast cancer. Cell cycle-related proteins would be helpful to determine the putative role of these markers in the process
of mammary carcinogenesis. The aim of this study was to analyze the expression of cell cycle related proteins in HUT of breast
specimens of patients with and without breast cancer, and compare this expression with areas of invasive carcinomas. |
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