Vaccination of mice against murine coccidiosis by ingestion of surface proteins of Eimeria falciformis incorporated in liposomes |
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| Authors: | A Rhalem K Bekhti C Bourdieu G Luffau P Péry |
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| Institution: | Station de Recherches de Virologie et d'Immunologie, I.N.R.A., Centre de Recherches de Jouy-en-Josas, Domaine de Vilvert. |
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| Abstract: | Proteins are released from the surface of sporozoites of Eimeria falciformis during their in vitro incubation in a detergent solution. Some of these proteins reacted with antibodies from infected mice and specifically stimulated the proliferation of mesenteric lymph node cells of these mice. Oral immunization of mice with liposome encapsulated sporozoite surface antigens protected mice against a challenge infection. Two proteins (M.W. 27 and 180 K) induced an antibody synthesis in these vaccinated mice. |
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