The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise |
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Authors: | Gonzalo Marañón Bárbara Muñoz-Escassi William Manley Cruz García Patricia Cayado Mercedes Sánchez de la Muela Begoña Olábarri Rosa León Elena Vara |
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Institution: | 1.Horsepital SL,Madrid,Spain;2.Departamento de Bioquímica y Biología Molecular. Facultad de Medicina,Universidad Complutense de Madrid,Madrid,Spain;3.Departamento de Medicina Animal y Cirugía. Facultad de Veterinaria,Universidad Complutense de Madrid,Madrid,Spain |
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Abstract: | Background Exercise induces changes in several organs and tissues, and this process might be due to oxidative damage caused by free radicals
and inflammatory mediators. Methyl Sulphonyl Methane, better known as MSM, is a naturally occurring sulphur compound with
well-known antioxidant properties. On the other hand, Vitamin C is important in limiting free radical damage in the aqueous
phase of the cell, and cellular vitamin C status may be linked to the mechanisms involved in quenching cellular reactive oxygen
species. The aim of this study was to determine if supplementation with MSM and vitamin C could alleviate exercise-induced
oxidative stress in horses undergoing jumping competition. |
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