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Fate by RNA methylation: m6A steers stem cell pluripotency
Authors:Boxuan Simen Zhao  Chuan He
Institution:Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, IL 60637 USA ;Howard Hughes Medical Institute, The University of Chicago, 929 East 57 Street, Chicago, IL 60637 USA
Abstract:The N6-methyladenosine (m6A) modification of mRNA has a crucial function in regulating pluripotency in murine stem cells: it facilitates resolution of naïve pluripotency towards differentiation.
Keywords:
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