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Suppression of angiotensin Ⅱ stimulated responses in aortic vascular smooth muscle cells of experimental cirrhotic rats
作者姓名:ZHANG RU  GUO LIANG WANG  PI LI ZHANG  YING XIONG  WEN BO ZHANG  XING PENG WANG  DE LING YIN  QING JING
作者单位:ZHANG RU; GUO LIANG WANG; PI LI ZHANG;YING XIONG; WEN BO ZHANG; XING PENG WANG; DE LING YIN; QING JING (Shanghai Institute of Cell Biology,Chinese Academy of Sciences,320 Yue Yang Road,Shanghai 200031,China
摘    要:INTRODUCTIONLivercirrhosisisoftencomplicatedbyhyperdynamiccirculation,whichischaracterizedbyadecreaseinarterialbloodpressureandperipheralvascularresistanceandanincreaseincardiacoutputandsplanchnicbloodnow1].Thesehaemodynamicdisturbancesareproposedtocontributetothedevelopmelltofportalhypertension,retentionofsodiumandwater,ascitesformationandcorrelatewithprognosisoflivercirrhosis2].Ithasbeensuggestedthatprimaryarterialvasodilationmayinducethishyperdynamiccirculation3].Buttheunderlyingmec…

关 键 词:Angiotensin    aortic  vascular  smooth  muscle  cells    cirrhosis  receptor  responses
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