| 钩虾胆碱酯酶（ChE）和谷胱甘肽转硫酶（GST）的敏感性和特异性比较研究 |
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| 引用本文： | 尹大强,金洪钧,于红霞,陈良燕.钩虾胆碱酯酶（ChE）和谷胱甘肽转硫酶（GST）的敏感性和特异性比较研究[J].应用生态学报,2001,12(4):615-618. |
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| 作者姓名： | 尹大强 金洪钧 于红霞 陈良燕 |
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| 作者单位： | [1]南京大学环境学院污染控制与资源化研究国家重点实验室，南京210093 [2]南京大学环境学院污染控制与资源化研究国 |
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| 基金项目： | 国家自然科学基金(39770153)和中英合作资助项目. |
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| 摘 要： | 研究了有机磷农药甲地基嘧啶流磷，有机氯农药林丹，菊酯类农药氯菊酯，表面活性剂直链苯磺酸钠和重金属Zn对钩虾（Gammarus pulex L.)胆碱酯酶（ChE）和谷胱甘肽转硫酶（GST）活性变化以及毒性影响，结果表明，在暴露24h和48h后，仅有机磷农药甲基嘧硫磷显著抑制胆碱酯的酶的活性，在暴露48h后，有机氯农药林丹和菊酯类农药氯菊酯能显著提高谷胱甘肽转硫酶活性，在暴露24h后，仅梵在导致谷胱甘肽转硫酶明显升高，作为生物标志物，胆碱酯酶比谷胱甘肽转硫酶具有更高的特异性，这两种生物标志物较毒性试验方法具有更高的敏感性。
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| 关 键 词： | 生态标志物 胆碱酯酶 谷胱甘肽转硫酶 钩虾 敏感性 农药 水生生态 |
| 文章编号： | 1001-9332(2001)04-0615-04 |
| 修稿时间： | 2000年6月5日 |
A comparative study on the sensitivity and specificity of cholinesterase and glutathione s-transferase in Gammarus |
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| YIN Daqiang,JIN Hongjun,YU Hongxia,CHEN Liangyan.A comparative study on the sensitivity and specificity of cholinesterase and glutathione s-transferase in Gammarus[J].Chinese Journal of Applied Ecology,2001,12(4):615-618. |
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| Authors: | YIN Daqiang JIN Hongjun YU Hongxia CHEN Liangyan |
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| Institution: | State Lab of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210093. yindq@nju.edu.cn |
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| Abstract: | Studies on the influences of lindane,pirimiphos methyl,permethrin,zinc and dodecyl linear alkybenzene sulfonate(LAS) on the activity and toxicity of cholinesterase (ChE) and glutathione s-transferase (GST) in Gammarus pulex L. showed that only pirimiphos methyl caused a change in ChE activity in Gammarus,with a significant reduction in enzyme activity after 24h and 48h exposure.Both lindane and permethrin caused a change in GST activity in Gammarus,with a significant increase in enzyme activity after 48h exposure.Lindane alos caused a significant increase in GST activity after 24h exposure.Biomarkers ChE and GST were demonstrated a high degree of specificity and sensiti- vity in comparison to the lethality assay,but GST activity was less specific than ChE activity. |
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| Keywords: | Biomarkers ChE GST Gammarus pulex L |
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