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聚氨酯/液晶(PU/EBBA)复合膜的血液相容性研究
引用本文:易正戟,周长忍.聚氨酯/液晶(PU/EBBA)复合膜的血液相容性研究[J].上海生物医学工程,2001,22(4):53-54.
作者姓名:易正戟  周长忍
作者单位:[1]广东省农业科学院前沿动物保健技术中心,广东510640 [2]暨南大学生物医学工程研究所,广东510632
摘    要:以聚氨酯弹性体为基质材料,与液晶化合物EBBA共混后,由溶剂蒸发法浇铸成膜。偏光显微镜观察证实了复合膜中液晶相的存在。用动态凝血实验、血小板粘附实验和扫描电镜观察的方法研究了复合膜中液晶含量对材料抗凝血性能的影响。结果表明,只有当液晶含量达到30%(wt)时,复合膜的血液相容性随着液晶含量的增加有明显改善,同时发现复合膜表面吸附的血小板随着液晶含量的增加而明显减少。

关 键 词:聚氨酯  4-乙氧基苄叉-4‘-正丁基苯胺  血液相容性  聚氨酯/液晶复合膜

Blood compatibility of polymer/liquid crystal (PU/EBBA) composite membranes
Qiayan Animal Health Technology Centre,Gaungdong Academy of Agricutural Science Yi Zhengji Institute of Biomedical Engineering,Jinan University Zhou Changren.Blood compatibility of polymer/liquid crystal (PU/EBBA) composite membranes[J].Shanghai Journal of Biomedical Engineering,2001,22(4):53-54.
Authors:Qiayan Animal Health Technology Centre  Gaungdong Academy of Agricutural Science Yi Zhengji Institute of Biomedical Engineering  Jinan University Zhou Changren
Abstract:In our work, polyurethene elastomers, as a substrate, were blended with N-(-4- ethoxybenzylidene )-4'-butylaniline and then crosslinked into membranes on glass plates by means of the platinum catalyst. The effects of liquid-crystal content in composite membranes on the formation of liquid-crystal phase were verified by the observation of optical polarization microscopy. The relationship between the morphology of the composite membranes and blood compatibility was identified by the dynamic-clotting test, platelet adhesion and SEM observation. The results show that the composite membranes appear to be beneficial to improve the blood compatibility when the liquid crystal content is higher than 30% and the platelet adhesion decreases with the increase of content of liquid crystal in composite membranes.
Keywords:Polyurethane Liquid crystal Composite membrane Blood Compatibility
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