Spectroscopic studies of the interaction of synthetic RNAs with quinacrine and its analogs. |
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| Authors: | S Nakamura S Yoshimatsu K Murakami Y Kubota |
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| Affiliation: | Department of Chemistry, Faculty of Science, Yamaguchi University, Japan. |
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| Abstract: | The interaction of synthetic RNAs with quinacrine (QAC) and its analogs has been studied by absorption, fluorescence and circular dichroism (CD) measurements. The results indicate that the 2-methoxy group of the acridine ring plays an important role in the appearance of the new absorption band upon binding of QAC to poly-(rA).poly(rU). |
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