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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging
Institution:1. Division of Regenerative Medicine, Department of Medicine, Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA;2. La Jolla Institute for Immunology, La Jolla, CA 92037, USA
Abstract:
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  • Keywords:stem cell  hematopoietic stem cell  stress  proteostasis  Hsf1  heat shock response  protein synthesis  translation  aging  hematopoiesis
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