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Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Affiliation:1. University of Minnesota, Department of Medicine, Minneapolis, MN 55455, USA;2. Fate Therapeutics, San Diego, CA 92121, USA;3. University of Minnesota, Department of Veterinary and Biomedical Sciences, St. Paul, MN 55108, USA;4. KG Jebsen Center for Cancer Immunotherapy, Institute of Clinical Medicine, University of Oslo, Oslo, Norway;5. Department of Cancer Immunotherapy, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway;6. Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden;7. University of Minnesota, Department of Pediatrics, Minneapolis, MN 55455, USA;8. Broegelmann Research Laboratory, Department of Clinical Sciences, University of Bergen, Bergen, Norway;9. Centre for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
Abstract:
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  • Keywords:natural killer cell  NK cell  induced pluripotent stem cell  iPSC  immunotherapy  adaptive  multiple myeloma  acute myeloid leukemia  off-the-shelf
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