Carbohydrates of the brown seaweed Dictyota dichotoma |
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Authors: | AFouad Abdel-Fattah MMagdel-Din Hussein STawheed Fouad |
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Institution: | Laboratory of Microbial Chemistry, National Research Centre, Dokki, Cairo, Egypt |
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Abstract: | The fucose-containing polysaccharides of the brown alga Dictyota dichotoma were extracted with either trichloroacetic acid or HCl to give both water-soluble and water-insoluble materials. The latter had a high proportion (16 to 11%) of protein, and although all the sugars found in the water-soluble extracts were present, the major sugar in these water-insoluble polysaccharides was glucose. The water-soluble material extracted with HCl was a protein-free sulphated heteropolysaccharide. Complete removal of a glucan from the water-soluble extract was achieved by fractional precipitation with ethanol. The recovered glucan-free sulphated polysaccharide, which was rich in glucuronic acid, galactose, fucose and sulphate, showed high anticoagulating activity. |
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Keywords: | Phaeophyceae brown seaweed heteropolysaccharide sulphate glucuronic acid galactose fucose glycoproteins |
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