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Facile biomimetic synthesis of costunolide-1,10-epoxide,santamarin and reynosin |
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| Authors: | Antonio Augusto S Rodrigues Marcos Garcia Jaime A Rabi |
| Institution: | Núcleo de Pesquisas de Produtos Naturais, Instituto de Ciências Biomédicas, Bloco H, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro ZC-32, Brasil |
| Abstract: | Reaction of costunolide with peracids yields costunolide-1,10-epoxide which undergoes ready cyclization to santamarin and reynosin. |
| Keywords: | Sesquiterpene lactone costunolide-1 10-epoxide santamarin reynosin synthesis |
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