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Exploiting the effects of high hydrostatic pressure in biotechnological applications |
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| Authors: | Vadim V Mozhaev Karel Heremans Johannes Frank Patrick Masson and Claude Balny |
| Institution: | a Institut National de la Santé et de la Recherche Médicale, INSERM U 128, Route de Mende, B.P. 5051, 34033, Montpellier cedex 1, France b Chemistry Department, Moscow State University, 119899, Moscow, Russia c Chemistry Department, Katholieke Universiteit Leuven, Celesijnenlaan 200 D, B-3001, Leuven, Belgium d Kluyver Laboratory for Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands e Unité de Biochimie, Service de Santé des Armées, Centre de Recherches Emile Bardé, 24 Avenue des Maquis du Grévisaudan, B.P. 87, 38702, La Tronche, France |
| Abstract: | Applying hydrostatic pressure to biological systems and processes can alter their characteristics. In addition to its use as a basic research tool for investigating the kinetics and thermodynamics of biological systems at the molecular level, the application of pressure is also being used to modify the properties of biological materials to preserve or improve their qualities. This article reviews the principles underlying the observed effects of applied pressure on biological systems, and discusses current and potential application of pressure in biotechnological processes. |
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