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Morphological changes in the filtration-reabsorption barrier of the remaining kidney after its denervation and disordered lymph outflow
Authors:V A Shakhlamov  B V Shutka
Abstract:An electron microscopical investigation on combined effect of denervation and disturbance of lymphatic outflow to structural elements of the FRB in the preserved kidney after contralateral nephrectomy has been performed on 20 mature white rats in 3, 30, 180, 360 days. In 3 days in the cellular components of the FRB cytoplasmic structures are at the state of functional strain and overstrain. Hemostasis is observed in glomeruli and in peritubular capillaries, as well as edema of the interstitial connective tissue. In 30 days certain signs of hyperplasia and hypertrophy of intracellular structures appear in the components of the FRB. However, later (in 180, 360 days) certain tendency to predominance of processes of functional strain in the intracellular structures with their certain destruction and reaction of the connective stroma is observed.
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