The effects of porcine follicular fluid in the postcastration rise of gonadotropins in the rabbit |
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| Authors: | N Patritti Laborde V Rettori R H Asch |
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| Institution: | 1. Department of Medicine The University of Utah School of Medicine Salt Lake City, Utah 84132, USA;2. Department of Obstetrics and Gynecology The University of Texas Health Science Center at San Antonio San Antonio, Texas 78284, USA |
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| Abstract: | The effects of repeated administration of porcine follicular fluid (PFF) on the follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels after castration were studied in rabbits. Steroid-free dextran-charcoal extracted PFF was administered to male and female adult rabbits at 0800 and 1600 h for four days immediately following castration. Serum levels of FSH and LH were measured before, during and after the PFF administration and compared to controls. A significant increase in FSH and LH was observed within 24 h following castration in the controls. In the PFF-treated group, a clear suppression of serum FSH levels was observed during PFF administration in both males and females. FSH concentrations returned to the control levels within 24 h after PFF withdrawal. Even through LH levels showed no differences during PFF injection, compared to controls, a significant increase was observed following discontinuation of PFF administration. |
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