Sister chromatid exchanges--a sensitive assay of agents damaging human chromosomes. |
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| Authors: | E Solomon M Bobrow |
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| Affiliation: | Genetics Laboratory, Department of Biochemistry, South Parks Road, Oxford (Great Britain) |
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| Abstract: | ![]()
Sister chromatid exchange frequencies in human lymphocyte chromosomes are greatly increased by alkylating agents, but ionizing radiation has little if any such effect. Scoring these exchanges may provide a useful technique for exploring the mechanisms of chromosome breakage and repair. |
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| Keywords: | BrdU 5-bromodeoxyuridine SCE sister chromatid exchanges |
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