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Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor
Authors:Mutsuko Kukimoto-Niino  Kengo Tsuda  Kentaro Ihara  Chiemi Mishima-Tsumagari  Keiko Honda  Noboru Ohsawa  Mikako Shirouzu
Affiliation:1. Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Kanagawa 230-0045, Japan;2. Division of Structural and Synthetic Biology, RIKEN Center for Life Science Technologies, Yokohama, Kanagawa 230-0045, Japan
Abstract:
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  • Keywords:crystal structure  molecular dynamics  GTPase  Rho  Rac  Cdc42  dedicator of cytokinesis  DOCK  GEF  DHR-2
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