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Ethnic groups and high sensitivity C-reactive protein in Israel |
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| Authors: | Ofir Wolach Yaron Arbel Michael Cohen Uri Goldbourt Uzi Rebhun Itzhak Shapira Shlomo Berliner Ori Rogowski |
| Affiliation: | a Department of Internal Medicine 'A', Rabin Medical Center, Beilinson Campus, Petach Tikva, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Israelb Department of Internal Medicine 'D', Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Israelc Division of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, Tel Aviv University, Israeld Division of Jewish Demography & Statistics, The A Harman Institute of Contemporary Jewry, The Hebrew University of Jerusalem, Israel |
| Abstract: | High-sensitivity C-reactive protein (hs-CRP) is a biomarker that correlates with atherothrombotic risk and outcome. hs-CRP is influenced by various modifiable and non-modifiable factors. We studied the relationship between ethnic background and hs-CRP level, among the Jewish population in Israel. A total of 3659 men and 2180 women were divided into two ethnic groups (Ashkenazi and Sephardic Jews), based on the knowledge of Jewish immigration patterns throughout the centuries. Mean hs-CRP levels were calculated for each group and were adjusted for various factors known to influence hs-CRP. Sephardic Jews were found to have higher adjusted mean hs-CRP levels (2.0 mg l-1 for men and 3.9 mg l-1 for women) compared with Ashkenazi Jews (1.5 mg l-1 for men and 2.9 mg l-1 for women). Ethnic background emerged as an independent significant predictor of hs-CRP levels. We demonstrated that ethnicity is an important factor when considering hs-CRP as a marker of atherothrombotic risk. |
| Keywords: | High-sensitivity C-reactive protein gender ethnicity Jewish |
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