Methods of simulating the behavior of granule cells in hippocampus based on informon theory

Postulated pathways between neurones in hippocampus are briefly described, as are experiments demonstrating potentiation. It is suggested that variable synapses between the perforant path and granule cells may be acting like informons, and that inhibitory synapses from basket cells to granule cells may be performing the associated function of reinforcement.Methods for simulating the behaviour of a granule/basket cell pair, based on these two hypotheses, are described; it is explained how such a system can be used to predict the behaviour of a population of cells if all granule cells and all basket cells are similarly excited. The limitations of the present simulation are pointed out; suggestions are made for the inclusion of further details in future work.