First report of the bla(OXA-58) gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil |
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| Authors: | Figueiredo Deuseli Quaresma de Santos Kátia Regina Netto Dos Pereira Eliezer Menezes Schuenck Ricardo Pinto Mendonça-Souza Cláudia Rezende Vieira de Teixeira Lúcia Martins Mondino Silvia Susana Bona de |
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| Affiliation: | Programa de Pós-Gradua??o em Patologia Clínica, Universidade Federal Fluminense, Niterói, RJ, Brasil. |
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| Abstract: | Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of bla(OXA-58) gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the bla(OXA-23-like), bla(OXA-24-like), bla(OXA-58-like) and bla(OXA-51-like) genes. The bla(OXA-58) and bla(OXA-23) genes were detected in one and three isolates, respectively. Sequencing of the bla(OXA-58-like) amplicon revealed 100% identity with the A. baumannii bla(OXA-58) gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil. |
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