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DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity |
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| Authors: | Shanzhong Gong Helen Hong Yu Kenneth A Johnson David W Taylor |
| Institution: | 1. Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA;2. Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA;3. Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX 78712, USA |
| Abstract: |  |
| Keywords: | Cas9 CRISPR sgRNA kinetics R-loop DNA cleavage |
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