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Derepression of the Iroquois Homeodomain Transcription Factor Gene IRX3 Confers Differentiation Block in Acute Leukemia |
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| Authors: | Tim D.D. Somerville Fabrizio Simeoni John A. Chadwick Emma L. Williams Gary J. Spencer Katalin Boros Christopher Wirth Eleni Tholouli Richard J. Byers Tim C.P. Somervaille |
| Affiliation: | 1. Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK;2. Department of Histopathology, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK;3. Applied Computational Biology and Bioinformatics Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester M20 4BX, UK;4. Department of Haematology, Manchester University NHS Foundation Trust, Manchester M13 9WL, UK |
| Abstract: |  |
| Keywords: | IRX3 HOXA9 acute myeloid leukemia acute lymphoblastic leukemia |
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