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Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis |
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| Authors: | Masako Uchii Tadafumi Tamura Toshio Suda Masakazu Kakuni Akira Tanaka Ichiro Miki |
| Affiliation: | (1) Pharmaceutical Research Center, Kyowa Hakko Kogyo Co., Ltd, 1188 Shimotogari, Nagaizumi, Sunto Shizuoka, 411-8731, Japan;(2) Present address: PhoenixBio Co., Ltd, 3-4-1 Kagamiyama, Higashi-Hiroshima Hiroshima, 739-0046, Japan;(3) Department of Pathology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke Tochigi, 329-0498, Japan |
| Abstract: | IntroductionFibroblast growth factor 8 (FGF8) is isolated as an androgen-induced growth factor, and has recently been shown to contribute to limb morphogenesis. The aim of the present study was to clarify the role of FGF8 in animal models of osteoarthritis (OA). |
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