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Effect of dehydrocorrine-cobalt complex on mitochondria
Authors:L L Kiseleva  G N Novodarova  M E Vol'pin  A D Vinogradov
Abstract:The effects of the decamethyloctadehydrocorrine-cobalt complex (Co-C) on respiration and the ATP-synthetase activity of rat liver mitochondria were investigated. The Co-C complex was found to be an effective shunt of the respiratory chain. It accepts electrons from ubiquinone and donates them directly to O2. The Co-C complex inhibits the ATPase and ATP-synthetase activities of mitochondria.
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