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Germinal and somatic mutation induction in Drosophila after treatment of larvae with tritiated water.
Authors:G Ribas  C Torres  M Batiste-Alentorn  N Xamena  A Creus  R Marcos
Institution:Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Abstract:The present study was carried out to evaluate the mutagenicity of tritium, administered as tritiated water, in Drosophila melanogaster. Larvae were fed on tritium-treated medium during their development. Germinal and somatic mutation induction was detected by means of the sex-linked recessive lethal and the wing spot tests, respectively. Our results show that beta-radiation from tritium is able to induce significant increases in the frequency of both germinal and somatic mutations.
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