Synthesis and antitumor activity of new retinobenzoic acids |
| |
| Authors: | Khandare Reena P Vaze Kedar R Bhat Sujata V |
| |
| Institution: | 1. Laboratory for Advanced Research in Natural and Synthetic Chemistry, V.?G. Vaze College, Mumbai University, Mithagar road, Mulund (East), Mumbai 400?081, India, (phone: +91?22?21631421 ext 113;2. fax: +91?22?21634262) |
| |
| Abstract: | New retinobenzoic acid derivatives have been synthesized starting from 1,2,3,4-tetrahydro-1,1,2,4,4,6-hexamethylnaphthalene and 1,1,2,3,3-pentamethylindane. Four of the synthetic compounds displayed potent cytotoxic activities in vitro against human breast cancer and leukemic cell lines. Thus, these molecules can be further evaluated for the treatment of human leukemia and breast cancer. |
| |
| Keywords: | Retinobenzoic acids Antitumor activity |
| 本文献已被 PubMed 等数据库收录！ |
|
