An imidazoline pseudodipeptide suitable for solid phase peptide synthesis. |
| |
| Authors: | R C Jones J Dickson |
| |
| Institution: | Chemistry Department, The Open University, Milton Keynes, UK. r.c.f.jones@lboro.ac.uk |
| |
| Abstract: | This paper describes the synthesis of two diastereoisomers of an imidazoline dipeptide mimetic (a 4,5 dihydroimidazole-4-carboxylic acid), suitably protected for incorporation into solid phase peptide synthesis (SPPS) using the Fmoc protocol, from a phenylalanine-derived thioimidate and an alpha,beta-diaminopropanoic acid ester, followed by protecting group manipulation. |
| |
| Keywords: | |
|
|
