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Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision
Authors:Siew Cheng Phua  Shuhei Chiba  Masako Suzuki  Emily Su  Elle C Roberson  Ganesh V Pusapati  Mitsutoshi Setou  Rajat Rohatgi  Jeremy F Reiter  Koji Ikegami  Takanari Inoue
Institution:1. Department of Cell Biology and Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;2. Laboratory of Biological Science, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan;3. Advanced Research Facilities and Services, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan;4. Department of Biochemistry and Biophysics and Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158, USA;5. Department of Cellular and Molecular Anatomy and International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan;6. Departments of Medicine and Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA
Abstract:
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  • Keywords:Primary cilia  decapitation  disassembly  cell-cycle entry  extracellular vesicles  ectosome  Inpp5e  F-actin  AurA  Gli  genetically encoded ciliary actin inhibitor
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