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Lymphocyte choriomeningitis virus plays hide-and-seek with type 1 interferon
Authors:Trinchieri Giorgio
Affiliation:Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. trinchig@mail.nih.gov
Abstract:In this issue, Macal et?al. (2012); Walsh et?al. (2012), and Wang et?al. (2012) examine how adaptive immune responses to acute and chronic lymphocyte choriomeningitis virus infection are regulated by type 1 interferon produced early during infection by different cell types upon activation by intracellular nucleic acid sensors.
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