(Na+,K+)-ATPase stimulation by sucrose feeding: prevention by 6-hydroxydopamine |
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Authors: | A C Swann |
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Institution: | Department of Psychiatry, University of Texas Medical School, P.O. Box 20708, Houston, Texas 77025, USA |
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Abstract: | The effects of sucrose feeding on parameters associated with (Na+,K+)-ATPase in brown adipose tissue were compared in rats treated with parenteral 6-hydroxydopamine and vehicle. Sucrose feeding significantly increased K+-p-nitrophenylphosphatase and ouabain binding in brown adipose tissue from rats treated with vehicle. By contrast, sucrose feeding had no effects on these measurements in rats treated with parenteral 6-hydroxydopamine. 6-hydroxydopamine did not significantly alter sucrose consumption and there were no significant effects on weight gain during the short experimental period. |
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