Cloning and expression of CSAL2, a new member of the spalt gene family in chick |
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| Authors: | Farrell E R Tosh G Church E Münsterberg A E |
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| Affiliation: | School of Life Sciences Biocentre, Division of Cell and Developmental Biology, University of Dundee, Wellcome Trust Biocenter, Dow Street, DD 1 5EH, Dundee, UK. |
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| Abstract: | ![]()
In this study we describe cloning and expression of CSAL2, a second member of the spalt gene family in chick. All spalt proteins are characterized by the presence of multiple zinc-finger motifs, which are highly conserved. Mutations in HSAL1, a human spalt gene result in Townes-Brocks syndrome (TBS). We show here that CSAL2 is expressed in many of the tissues affected in TBS, including neural tissue, limb buds, mesonephros and cloaca. |
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