Remobilization of Tol2 transposons in Xenopus tropicalis |
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| Authors: | Donald A Yergeau Clair M Kelley Emin Kuliyev Haiqing Zhu Amy K Sater Dan E Wells Paul E Mead |
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| Affiliation: | (1) Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA;(2) Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA |
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| Abstract: | Background The Class II DNA transposons are mobile genetic elements that move DNA sequence from one position in the genome to another. We have previously demonstrated that the naturally occurring Tol2 element from Oryzias latipes efficiently integrates its corresponding non-autonomous transposable element into the genome of the diploid frog, Xenopus tropicalis. Tol2 transposons are stable in the frog genome and are transmitted to the offspring at the expected Mendelian frequency. |
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